Haematology and Leukaemia MPhil

University of Liverpool

Undertake research that will make a significant impact on strategies to detect, stratify and treat patients with a range of blood cancers on this Haematology and Leukaemia research degree.IntroductionHaemato-oncology is one of Liverpool’s recognised academic strengths. Focused on therapy failure due to resistance or intolerance, our research in haematology and leukaemia:Encompasses laboratory, clinical, health data and cross-disciplinary approachesExploits our unique platform technologies, sample collections and datasetsIncorporates strong patient involvement and integration with the regional clinical and diagnostic service.This research takes a variety of forms:Laboratory research – identifying biological factors that influence treatment outcomes. Scientific themes are B cell receptor signalling, 17p aberrations, non-coding RNAs and non-malignant T cells. Projects are enabled by our unique sample collections which are linked to multiple clinical trials and observational studiesClinical research – evaluating blood cancer treatment in selected patient cohorts. We lead several national clinical trials and observational studies in chronic lymphocytic leukaemia (CLL), follicular lymphoma and diffuse large B cell lymphomaHealth data research – understanding blood cancer treatment at population level. We lead UNCOVER, a national health data research programme that uses routinely collected NHS data from approximately 300,000 patients with all types of blood cancerCross-disciplinary research – research involving blood cancer and other specialties. We are co-leading multiple areas of collaborative research involving molecular diagnostics, imaging, drug safety science, cardiology and infectious diseases.