Pharmacology and Drug Discovery PhD

University of Nottingham

Your research degree is bespoke at the University of Nottingham, and allows you to choose your own area of interest to research, under the title of your choosing. Our Pharmacology and Drug Discovery grouping is made up of the following available PhD and MRes courses:Pharmacology Clinical Chemistry Cell Signalling Molecular Pharmacology and Drug Discovery Our supervisors in the school are at the forefront of research in their fields. Utilising industry standard facilities, along with cutting edge equipment, and the guidance of our supervisors, you will advance the area of life sciences that interests you.Your degree and research area is bespoke to you, however, here are some examples of the research we already conduct within the Pharmacology and Drug Discovery fields:Understanding the genetic basis of Alzheimer's diseaseMolecular Pharmacology and Cell Biology of Cell Surface Receptors: molecular pharmacology, regulation and signalling of G-protein-coupled receptors and tyrosine kinase-linked receptors.'Cross-Talk' Between Different Intracellular Pathways: synergistic interactions between G-protein-coupled receptors (GPCRs); interactions between GPCRs and tyrosine kinase receptors; cross-cascade signalling of proteins involved in gene transcription.Single molecule analysis of ligand-receptor interactions using fluorescence correlation spectroscopy: research on the development of fluorescent ligands for GPCRs.Use of bimolecular fluorescence complementation to investigate protein-protein interactions: investigation of receptor trafficking and receptor-effector interactions