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Concept to Clinic (S827) Credits from The Open University

Concept to Clinic (S827) Credits from The Open University

Key information

Qualification type

Credits from The Open University

Subject areas


Course type


Course Summary

This course provides an overview of the drug discovery and development process from a modern and historical perspective, exemplified by the design and development of current and future therapeutic drugs for pain and inflammation. You will be introduced to a range of issues in drug discovery, from the initial concept of selecting a disease, a disease target and the type of molecules to be utilised, to evaluating their properties, identifying lead compounds and developing these into commercial drug products. You will mainly work independently with online support although you will have an opportunity to collaborate in group-work activities.

The aims of the module are to: provide a clear understanding of what a drug is required to do in terms of reaching and interacting with its molecular target and having a consequent influence on the course of a disease; develop a clear understanding of drug metabolism and pharmacokinetics (DMPK) and absorption, distribution, metabolism, excretion, toxicology (ADMET) concepts through the science behind DMPK and the role of ADMET properties in the fate of an administered drug dose; develop an understanding of the relationship of molecular properties to the pharmacokinetic profiles of those compounds and broaden understanding of wider concepts in lead optimisation and to get a flavour of contemporary thinking and methodology used to speed up the process and enhance success rates. You will be expected to submit your tutor-marked assignments (TMAs) online through the eTMA system unless there are some difficulties which prevent you from doing so. In these circumstances, you must negotiate with your tutor to get their agreement to submit your assignment on paper. There is an interactive computer-marked assignment (iCMA) which covers the general medicinal chemistry and drug design themes, and three TMAs which cover the specific disease therapies. One of the TMAs relates to a group-work presentation (which you will present online).

Different course options

Study mode

Distance without attendance


6 months

Start date


Tuition fees

UK fees
Course fees for UK / EU students

For this course (overall cost)


Average for all Postgrad courses (per year)


International fees
Course fees for non-UK / EU students

Not known

Average for all Postgrad courses (per year)


Entry requirements

Students must normally hold a UK honours degree (or equivalent qualification) in science or a science-related subject. An undergraduate degree in the areas of chemistry, physics, biology and medicine would be preferred. As this module deals with medicinal chemistry, knowledge of chemistry, and especially organic chemistry, would be particularly helpful. If you have other study or experience that you believe equips you to study at postgraduate level you can still apply, but must supply evidence of that study or experience. Your case will be referred to our MSc in Science Admissions Panel. You will need good computing skills (e.g. able to search the Web, use email, use word processing packages, use spreadsheet packages to perform calculations and produce graphs and use presentation software to produces slides). You should also be able to carry out mathematical manipulations (e.g. algebraic rearrangement of equations, use exponentials and logs).