Our work in this area covers the processes of cardiac remodelling and repair in health and disease. Cardiac adaptions through remodelling and repair occur at multiple levels and throughout life. One
We explore changes in the nervous, cardiorespiratory, vascular, and muscular systems to uncover the fundamental mechanisms at rest and during exercise that maintain health and performance, and drive
Lifestyle-related diseases such as obesity, cancer and metabolic diseases represent a global challenge to human health and wellbeing. Our research focuses on the relationship between the food we eat
Contraction of cardiac and skeletal muscle depends on the precise arrangement and interaction of elements of the excitation-contraction machinery and of the signalling pathways that regulate these.
We study many elements of health and disease, striving to improve lifelong health and wellbeing in animals and humans from early development through to aging. Subjects studied include protein-protein
Skeletal muscle is vital for life, underpinning locomotion, respiration, and metabolism, yet we still poorly understand its response to exercise and disease. Our research focuses on skeletal muscle
Cardiac arrhythmias occur when the heart’s electrical activity becomes chaotic and it can no longer pump blood efficiently. Ageing, certain conditions such as heart failure, and even intense exercise